projects:
GABAARs, the HPA Axis, and Postpartum Depression Stress and GABAARs GABAARs, Aging, and Anxiety Epilepsy and Depression
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relevant publications:
Sarkar J, Wakefield S, MacKenzie G, Moss SJ, and Maguire J. (2011) Neurosteroidogenesis Is Required for the Physiological Response to Stress: Role of Neurosteroid-Sensitive GABAA Receptors. J Neurosci.;31(50):18198-210.
Delia Belelli, Neil L. Harrison, Jamie Maguire, Robert L. Macdonald, Matthew C. Walker, and David W. Cope (2009) Extrasynaptic GABAA Receptors: Form, Pharmacology, and Function J Neurosci.;29(41):12757-12763.
Maguire, J.L., Ferando, I., Simonsen, C., and Mody, I. (2009) Excitability changes related to GABAA receptorplasticity during pregnancy. J Neurosci.;29 9592-9601.
Maguire, J.L.and Mody, I. (2009) Steroid hormone fluctuations and GABAAR plasticity. Psychoneuroendocrinology. Jul 23. [Epub ahead of print].
Maguire, J.L.and Mody, I. (2008) GABA(A)R plasticity during pregnancy: relevance to postpartum depression. Neuron. 59(2):207-13
Maguire, J.L. and Mody, I. (2007) Neurosteroid Synthesis-Mediated Regulation of GABAA Receptors: Relevance to Ovarian Cycle and Stress. J Neurosci. 27(9):2155–2162.
Klaassen A, Glykys J, Maguire J, Labarca C, Mody I, Boulter J. (2006) Seizures and enhanced cortical GABAergic inhibition in two mouse models of human autosomal dominant nocturnal frontal lobe epilepsy. Proc Natl Acad Sci USA. 103(50):19152-19157.
Maguire, J.L., Stell, B.M., Rafizadeh, M., and Mody, I. (2005) Ovarian cycle-linked changes in GABAA receptors mediating tonic inhibition alter seizure susceptibility and anxiety. Nature Neurosci Jun;8(6):797-804.